Laboratory of Natural Product Biosynthesis Systems
Laboratory was established in 2009 году
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Group of Dr. Yuriy Sheludko performs researches in area of plant natural product biosynthesis. It includes studies on production of recombinant proteins in plants using transient and constitutive foreign gene expression. The aim of studies is understanding of transgene expression mechanisms in different types of plant systems (including undifferentiated cell cultures and transgenic hairy roots), selection of transgenic plants with agriculture valuable characteristics and development of biotechnological protocols for production of pharmaceutical proteins or plant based vaccines. The modern methods of molecular and cell biology and recombinant DNA protocols are applied for expression vector construction and foreign DNA introduction into plant cell. Additionally, investigation of secondary metabolism in plants or in vitro cell systems of pharmacologically valuable species (Rauvolfia serpentina, Psoralea drupaceae etc.), isolation, purification and identification of single compounds and enzymes is a focus of researches. Group studies influence of elicitors and stress factors on accumulation of secondary metabolites. In the course of researches a wide variety of analytical technologies are applied including HPLC, FPLC, flash chromatography, analytical and preparative thin layer chromatography and spectroscopy methods.
Laboratory Presentation
Structure:
Head of laboratory, PhD,Yurij V. Sheludko
Scientific associate, PhD, Iryna M. Gerasymenko
Scientific associate, PhD, Yana R. Sindarovska
Principal engineer Maria G. Mazur
PhD student, 1st rank engineer(1/2 rate) Tatiana M. Kyrpa
